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Darbepoetin

Aranesp

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Endocrine

Routes

SCIV

Indications

Anemia of chronic kidney disease

Mechanism of Action

Hyperglycosylated analog of erythropoietin with longer half-life. Stimulates red blood cell production from erythroid progenitor cells.

Side effects & warnings

Monitor PCV/HCT closely. Risk of pure red cell aplasia from antibody formation. Supplement iron. Avoid if PCV rising too rapidly.

Species with Darbepoetin dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0.001 mcg/kgq1-2 weeksModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)SC0.001 mcg/kgq1-2 weeksModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Darbepoetin