Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Clofazimine is dosed at 4–8 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.288, Clofazimine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Clofazimine is used in dogs for Mycobacterial infections (atypical). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Clofazimine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lamprene
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 4–8 mg/kg | q24h | Months (as part of combination therapy) | Mycobacterial infections (atypical) | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.288, Clofazimine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4–8 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.109 | 4-8 mg/kg p.o. q24h for 2-6 months. For the management of mycobacterial infections, the drug is gen |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds to mycobacterial DNA and generates reactive oxygen species. Also has anti-inflammatory properties via inhibition of phospholipase A2.
Red-brown skin discoloration. GI upset, especially at higher doses. Crystal deposition in tissues with long-term use.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Clofazimine dose range in dogs, with cited source references: PO 4–8 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Clofazimine in dogs: PO.
Cited course lengths for Clofazimine in dogs include: Months (as part of combination therapy). Duration depends on the indication — match it to the specific dose rule in the table above.
Clofazimine is indicated in dogs for: Mycobacterial infections (atypical).
These are general warnings for Clofazimine across species; consult the dog dosing table above for species-specific guidance. Red-brown skin discoloration. GI upset, especially at higher doses. Crystal deposition in tissues with long-term use.
Why a species-specific page? Clofazimine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.