Cat · Felis catus · typical adult weight 2.50–7.00 kg
Clofazimine is dosed at 2–8 mg/kg PO q24-48h in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.288, Clofazimine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Clofazimine is used in cats for Mycobacterial infections (feline leprosy, atypical). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Clofazimine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lamprene
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–8 mg/kg | q24-48h | Months (combination therapy) | Mycobacterial infections (feline leprosy, atypical) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.288, Clofazimine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4–8 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.109 | 4-8 mg/kg p.o. q24h for 2-6 months. For the management of mycobacterial infections, the drug is gen |
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.201 | • 1 mg/kg up to a maximum of 4 mg/kg/day PO. |
| 4 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.201 | • 1 mg/kg up to a maximum of 4 mg/kg/day PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds to mycobacterial DNA and generates reactive oxygen species. Also has anti-inflammatory properties via inhibition of phospholipase A2.
Red-brown skin discoloration. GI upset, especially at higher doses. Crystal deposition in tissues with long-term use.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Clofazimine dose range in cats, with cited source references: PO 2–8 mg/kg q24-48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Clofazimine in cats: PO.
Cited course lengths for Clofazimine in cats include: Months (combination therapy). Duration depends on the indication — match it to the specific dose rule in the table above.
Clofazimine is indicated in cats for: Mycobacterial infections (feline leprosy, atypical).
These are general warnings for Clofazimine across species; consult the cat dosing table above for species-specific guidance. Red-brown skin discoloration. GI upset, especially at higher doses. Crystal deposition in tissues with long-term use.
Why a species-specific page? Clofazimine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.