Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dorzolamide-Timolol Ophthalmic is used in dog for Glaucoma (IOP reduction). Routes documented in dog: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dorzolamide-Timolol Ophthalmic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cosopt
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | 0 1 drop per eye | q8-12h | Long-term glaucoma management | Glaucoma (IOP reduction) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Dorzolamide inhibits carbonic anhydrase in ciliary body, reducing aqueous humor production. Timolol is a beta-blocker reducing aqueous production via different mechanism. Additive IOP-lowering.
Contraindicated with systemic beta-blockers (additive bradycardia). Avoid in cats with asthma. Local stinging common. Monitor IOP response.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Dorzolamide-Timolol Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.