Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dorzolamide-Timolol Ophthalmic is used in dogs for Glaucoma (IOP reduction). Routes documented in dogs: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dorzolamide-Timolol Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cosopt
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | Additive IOP-lowering effect | q8-12h | Long-term glaucoma management | Glaucoma (IOP reduction) | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1389 (2026-08-01). |
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Dorzolamide inhibits carbonic anhydrase in ciliary body, reducing aqueous humor production. Timolol is a beta-blocker reducing aqueous production via different mechanism. Additive IOP-lowering.
Contraindicated with systemic beta-blockers (additive bradycardia). Avoid in cats with asthma. Local stinging common. Monitor IOP response.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dorzolamide-Timolol Ophthalmic dose range in dogs, with cited source references: TOPICAL (ophthalmic) Additive IOP-lowering effect q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dorzolamide-Timolol Ophthalmic in dogs: TOPICAL (ophthalmic).
Cited course lengths for Dorzolamide-Timolol Ophthalmic in dogs include: Long-term glaucoma management. Duration depends on the indication — match it to the specific dose rule in the table above.
Dorzolamide-Timolol Ophthalmic is indicated in dogs for: Glaucoma (IOP reduction).
These are general warnings for Dorzolamide-Timolol Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Contraindicated with systemic beta-blockers (additive bradycardia). Avoid in cats with asthma. Local stinging common. Monitor IOP response.
Why a species-specific page? Dorzolamide-Timolol Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.