Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Polysulfated Glycosaminoglycan is used in dog for Osteoarthritis. Routes documented in dog: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Polysulfated Glycosaminoglycan in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Adequan Canine, Adequan Equine
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 4.4 mg/kg | q3-5 days x 8 injections | 8-injection series | Osteoarthritis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits catabolic enzymes (metalloproteinases, serine proteases) in cartilage. Stimulates proteoglycan and hyaluronic acid synthesis. Anti-inflammatory in joints.
FDA-approved for dogs and horses. IM injection series (usually 8 doses over 4 weeks). May affect coagulation — avoid in patients on anticoagulants. Injection site reactions.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Polysulfated Glycosaminoglycan pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.