Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ursodiol is dosed at 10–15 mg/kg PO q24h in dogs, per Watson PJ. Chapter 142: Chronic Hepatitis Therapy. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:583-587. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01).. Ursodiol is used in dogs for Chronic hepatitis, gallbladder mucocele, cholangitis. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ursodiol in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Actigall, Ursodex
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–15 mg/kg | q24h | Long-term | Chronic hepatitis, gallbladder mucocele, cholangitis | Moderate | Watson PJ. Chapter 142: Chronic Hepatitis Therapy. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:583-587. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Hydrophilic bile acid that displaces toxic hydrophobic bile acids from the bile acid pool. Choleretic, hepatoprotective, and immunomodulatory effects.
Give with food. Monitor liver enzymes. CONTRAINDICATED in complete biliary obstruction. Generally well-tolerated. Used in cholangiohepatitis, gallbladder mucocele, chronic hepatitis.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ursodiol dose range in dogs, with cited source references: PO 10–15 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ursodiol in dogs: PO.
Cited course lengths for Ursodiol in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Ursodiol is indicated in dogs for: Chronic hepatitis, gallbladder mucocele, cholangitis.
These are general warnings for Ursodiol across species; consult the dog dosing table above for species-specific guidance. Give with food. Monitor liver enzymes. CONTRAINDICATED in complete biliary obstruction. Generally well-tolerated. Used in cholangiohepatitis, gallbladder mucocele, chronic hepatitis.
Why a species-specific page? Ursodiol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.