ExoticRx · exoticrx.com/drugs/ursodiol
US brand names:Actigall, Ursodex
Ursodiol is dosed at 15 mg/kg PO q12h in ferrets, per Burgess M, Garner M. Clinical aspects of inflammatory bowel disease in ferrets. Exot DVM. 2002;4(2):29-34. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.959 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.10 (Miscellaneous Agents Used in Ferrets.a). Verify against current literature before clinical use.
Hydrophilic bile acid that displaces toxic hydrophobic bile acids from the bile acid pool. Choleretic, hepatoprotective, and immunomodulatory effects.
Give with food. Monitor liver enzymes. CONTRAINDICATED in complete biliary obstruction. Generally well-tolerated. Used in cholangiohepatitis, gallbladder mucocele, chronic hepatitis.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Ferret drugs
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A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 10–15 mg/kg | q24h | Moderate | Twedt DC, Armstrong PJ, Simpson KW. Chapter 150: Feline Cholangitis. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:614-621. — Plumb's 10th ed printed p.1288, Ursodiol monograph spanning p.1287-1288.Compilation only — we have not located an independent source that prints this figure. |
| Dog (Domestic) | PO | 10–15 mg/kg | q24h | Moderate | Watson PJ. Chapter 142: Chronic Hepatitis Therapy. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:583-587. — Plumb's 10th ed printed p.1288, Ursodiol monograph spanning p.1287-1288.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.