Cat · Felis catus · typical adult weight 2.50–7.00 kg
Ursodiol is dosed at 10–15 mg/kg PO q24h in cats, per Twedt DC, Armstrong PJ, Simpson KW. Chapter 150: Feline Cholangitis. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:614-621. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01).. Ursodiol is used in cats for Cholangiohepatitis, hepatic lipidosis support. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Ursodiol in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Actigall, Ursodex
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–15 mg/kg | q24h | Long-term | Cholangiohepatitis, hepatic lipidosis support | Moderate | Twedt DC, Armstrong PJ, Simpson KW. Chapter 150: Feline Cholangitis. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:614-621. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01). |
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Hydrophilic bile acid that displaces toxic hydrophobic bile acids from the bile acid pool. Choleretic, hepatoprotective, and immunomodulatory effects.
Give with food. Monitor liver enzymes. CONTRAINDICATED in complete biliary obstruction. Generally well-tolerated. Used in cholangiohepatitis, gallbladder mucocele, chronic hepatitis.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ursodiol dose range in cats, with cited source references: PO 10–15 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ursodiol in cats: PO.
Cited course lengths for Ursodiol in cats include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Ursodiol is indicated in cats for: Cholangiohepatitis, hepatic lipidosis support.
These are general warnings for Ursodiol across species; consult the cat dosing table above for species-specific guidance. Give with food. Monitor liver enzymes. CONTRAINDICATED in complete biliary obstruction. Generally well-tolerated. Used in cholangiohepatitis, gallbladder mucocele, chronic hepatitis.
Why a species-specific page? Ursodiol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.