Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sodium Bicarbonate is dosed at 1–2 mEq/kg IV IV slowly over 15-30 min in dogs, per Fletcher DJ, Boller M, Brainard BM, et al. RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 7: Clinical guidelines. J Vet Emerg Crit Care. 2012;22(s1):S102-S131. doi:10.1111/j.1476-4431.2012.00751.x; Drobatz KJ. Emergencies of the urogenital tract. Presented at: International Veterinary Emergency and Critical Care Symposium; 2009. PMID: 41518235; Cooper E, Scansen BA. Chapter 122: Obstructive Uropathy. In: Bruyette D, ed. Clinical Small Animal Internal Medicine. John Wiley & Sons, Inc.; 2020:1109-1122. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1189 (2026-08-01).. Sodium Bicarbonate is used in dogs for Severe metabolic acidosis (pH <7.1), Urinary alkalinization. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Sodium Bicarbonate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: NaHCO3
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–2 mEq/kg | IV slowly over 15-30 min | Until pH corrected | Severe metabolic acidosis (pH <7.1) | Moderate | Fletcher DJ, Boller M, Brainard BM, et al. RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 7: Clinical guidelines. J Vet Emerg Crit Care. 2012;22(s1):S102-S131. doi:10.1111/j.1476-4431.2012.00751.x; Drobatz KJ. Emergencies of the urogenital tract. Presented at: International Veterinary Emergency and Critical Care Symposium; 2009. PMID: 41518235; Cooper E, Scansen BA. Chapter 122: Obstructive Uropathy. In: Bruyette D, ed. Clinical Small Animal Internal Medicine. John Wiley & Sons, Inc.; 2020:1109-1122. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1189 (2026-08-01). |
| PO | 25–50 mg/kg | q8-12h | Variable | Urinary alkalinization | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Provides bicarbonate ions to buffer hydrogen ions. Raises blood pH. Shifts potassium intracellularly. Alkalinizes urine.
Use cautiously — overshoot alkalosis, hypernatremia, hypokalemia, decreased ionized calcium. Paradoxical CNS acidosis. Not routine in CPR. Monitor blood gases and electrolytes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sodium Bicarbonate dose ranges in dogs, with cited source references: IV 1–2 mEq/kg IV slowly over 15-30 min; PO 25–50 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sodium Bicarbonate in dogs: IV, PO.
Cited course lengths for Sodium Bicarbonate in dogs include: Until pH corrected; Variable. Duration depends on the indication — match it to the specific dose rule in the table above.
Sodium Bicarbonate is indicated in dogs for: Severe metabolic acidosis (pH <7.1), Urinary alkalinization.
These are general warnings for Sodium Bicarbonate across species; consult the dog dosing table above for species-specific guidance. Use cautiously — overshoot alkalosis, hypernatremia, hypokalemia, decreased ionized calcium. Paradoxical CNS acidosis. Not routine in CPR. Monitor blood gases and electrolytes.
Why a species-specific page? Sodium Bicarbonate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.