Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pilocarpine Ophthalmic is used in dogs for Glaucoma (miotic therapy). Routes documented in dogs: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pilocarpine Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Isopto Carpine
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | 1-2% solution | q6-8h | Continuous; until IOP controlled | Glaucoma (miotic therapy) | Moderate | Dodi PL. Immune-mediated keratoconjunctivitis sicca in dogs: current perspectives on management. Vet Med (Auckl). 2015;6:341-347. doi:10.2147/vmrr.s66705 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1422 (2026-08-01). |
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Direct-acting parasympathomimetic that contracts ciliary muscle and iris sphincter, causing miosis and opening trabecular meshwork to increase aqueous outflow.
Causes miosis, brow ache (in humans), and potential systemic cholinergic effects. Mostly replaced by latanoprost for glaucoma. May worsen uveitis.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pilocarpine Ophthalmic dose range in dogs, with cited source references: TOPICAL (ophthalmic) 1-2% solution q6-8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pilocarpine Ophthalmic in dogs: TOPICAL (ophthalmic).
Cited course lengths for Pilocarpine Ophthalmic in dogs include: Continuous; until IOP controlled. Duration depends on the indication — match it to the specific dose rule in the table above.
Pilocarpine Ophthalmic is indicated in dogs for: Glaucoma (miotic therapy).
These are general warnings for Pilocarpine Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Causes miosis, brow ache (in humans), and potential systemic cholinergic effects. Mostly replaced by latanoprost for glaucoma. May worsen uveitis.
Why a species-specific page? Pilocarpine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.