ExoticRx · exoticrx.com/drugs/pilocarpine-ophthalmic
US brand names:Isopto Carpine
Warnings from the source rows
Direct-acting parasympathomimetic that contracts ciliary muscle and iris sphincter, causing miosis and opening trabecular meshwork to increase aqueous outflow.
Causes miosis, brow ache (in humans), and potential systemic cholinergic effects. Mostly replaced by latanoprost for glaucoma. May worsen uveitis.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | TOPICAL (ophthalmic) | May combine with beta-blockers | q6-8h | Moderate | Dodi PL. Immune-mediated keratoconjunctivitis sicca in dogs: current perspectives on management. Vet Med (Auckl). 2015;6:341-347. doi:10.2147/vmrr.s66705 — Plumb's 10th ed printed p.1394, Pilocarpine Ophthalmic monograph. — Plumb's Veterinary Drug Handbook, 10th ed, Pilocarpine Ophthalmic monograph, printed p.1395: "Primary glaucoma (extra-label): 1 drop of pilocarpine 1% or 2% solution in the affected eye(s) 3 […]"; contraindication from the facing page, printed p.1394: "Contraindicated in cases of secondary glaucoma (eg, caused by uveitis or lens luxation) because of […]" |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.