Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cannabidiol (CBD) is dosed at 2–2.5 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted), Cannabidiol (CBD), printed p.181 (PDF p.208) — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 2 — "2 mg/kg PO, OTM every 12 hours2 concentration.13,38,39" — which resolves in the monograph's own reference list to: Brioschi FA, Cesare FD, Gioeni D, et al. Oral transmucosal cannabidiol oil Formulation as part of a multimodal analgesic regimen: effects on pain relief and quality of life improvement in dogs affected by spontaneous osteoarthritis. Animals (Basel). 2020;10. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.. Cannabidiol (CBD) is used in dogs for Osteoarthritis pain and epilepsy (adjunct to current therapy). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Cannabidiol (CBD) in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: ElleVet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–2.5 mg/kg | q12h | Long-term as supplement | Osteoarthritis pain and epilepsy (adjunct to current therapy) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted), Cannabidiol (CBD), printed p.181 (PDF p.208) — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 2 — "2 mg/kg PO, OTM every 12 hours2 concentration.13,38,39" — which resolves in the monograph's own reference list to: Brioschi FA, Cesare FD, Gioeni D, et al. Oral transmucosal cannabidiol oil Formulation as part of a multimodal analgesic regimen: effects on pain relief and quality of life improvement in dogs affected by spontaneous osteoarthritis. Animals (Basel). 2020;10. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Interacts with endocannabinoid system (CB1/CB2 receptors), TRPV1, 5-HT1A, and GPR55 receptors. Anti-inflammatory, analgesic, anxiolytic, and anticonvulsant properties.
Elevates ALP in dogs. Drug interactions with CYP450 substrates (NSAIDs, phenobarbital). Quality varies widely. THC content must be <0.3%. Not FDA-approved for veterinary use.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cannabidiol (CBD) dose range in dogs, with cited source references: PO 2–2.5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cannabidiol (CBD) in dogs: PO.
Cited course lengths for Cannabidiol (CBD) in dogs include: Long-term as supplement. Duration depends on the indication — match it to the specific dose rule in the table above.
Cannabidiol (CBD) is indicated in dogs for: Osteoarthritis pain and epilepsy (adjunct to current therapy).
These are general warnings for Cannabidiol (CBD) across species; consult the dog dosing table above for species-specific guidance. Elevates ALP in dogs. Drug interactions with CYP450 substrates (NSAIDs, phenobarbital). Quality varies widely. THC content must be <0.3%. Not FDA-approved for veterinary use.
Why a species-specific page? Cannabidiol (CBD) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.