Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cobalamin is dosed at 250–1000 mcg per dog SC q7 days x 6 weeks, then monthly in dogs, per Ruaux CG. Cobalamin in companion animals: Diagnostic marker, deficiency states and therapeutic implications. Vet J. 2013;196(2):145-152. doi:10.1016/j.tvjl.2013.01.025; Steiner J. Cobalamin information. Texas A&M Veterinary Medicine and Biomedical Sciences; http://vetmed.tamu.edu/gilab/research/cobalamin-information#dosing. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.332 (2026-08-01).. Cobalamin is used in dogs for Cobalamin deficiency (EPI, GI disease). Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Cobalamin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cyanocobalamin, Hydroxocobalamin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 250–1000 mcg per dog | q7 days x 6 weeks, then monthly | Long-term | Cobalamin deficiency (EPI, GI disease) | Strong | Ruaux CG. Cobalamin in companion animals: Diagnostic marker, deficiency states and therapeutic implications. Vet J. 2013;196(2):145-152. doi:10.1016/j.tvjl.2013.01.025; Steiner J. Cobalamin information. Texas A&M Veterinary Medicine and Biomedical Sciences; http://vetmed.tamu.edu/gilab/research/cobalamin-information#dosing. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.332 (2026-08-01). |
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Enter your dog's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Essential cofactor for methionine synthase and methylmalonyl-CoA mutase. Required for DNA synthesis, erythropoiesis, and neurological function.
Commonly deficient in cats with GI disease (IBD, lymphoma, EPI). SC injection q1-4 weeks or daily high-dose oral. Very safe — water-soluble, excess excreted renally. Monitor serum levels.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cobalamin dose range in dogs, with cited source references: SC 250–1000 mcg per dog q7 days x 6 weeks, then monthly. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cobalamin in dogs: SC.
Cited course lengths for Cobalamin in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Cobalamin is indicated in dogs for: Cobalamin deficiency (EPI, GI disease).
These are general warnings for Cobalamin across species; consult the dog dosing table above for species-specific guidance. Commonly deficient in cats with GI disease (IBD, lymphoma, EPI). SC injection q1-4 weeks or daily high-dose oral. Very safe — water-soluble, excess excreted renally. Monitor serum levels.
Why a species-specific page? Cobalamin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.