Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Omega-3 Fatty Acids is dosed at 50–100 mg/kg EPA+DHA PO q24h with food in dogs, per Freeman LM. Beneficial effects of omega-3 fatty acids in cardiovascular disease. J Small Anim Pract. 2010;51(9):462-470. doi:10.1201/9780429402180-1 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.530 (2026-08-01). — Plumb's 10th ed (held) printed p.501, Fatty Acids, Omega-3 monograph spanning p.501-502; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.683, Interferon Omega, Feline Origin monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Omega-3 Fatty Acids is used in dogs for Anti-inflammatory (skin, joints, renal, cardiac), Atopic dermatitis, OA, CKD (anti-inflammatory). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Omega-3 Fatty Acids in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Welactin, Dermaquin, Free Form Omega-3, Fish Oil (EPA/DHA)
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 50–100 mg/kg EPA+DHA | q24h with food | Long-term daily supplementation; 4-6 weeks for noticeable effect | Anti-inflammatory (skin, joints, renal, cardiac) | Moderate | Freeman LM. Beneficial effects of omega-3 fatty acids in cardiovascular disease. J Small Anim Pract. 2010;51(9):462-470. doi:10.1201/9780429402180-1 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.530 (2026-08-01). — Plumb's 10th ed (held) printed p.501, Fatty Acids, Omega-3 monograph spanning p.501-502; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.683, Interferon Omega, Feline Origin monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 40–100 mg/kg | q24h | Long-term | Atopic dermatitis, OA, CKD (anti-inflammatory) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.501, Fatty Acids, Omega-3 monograph spanning p.501-502; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
EPA and DHA compete with arachidonic acid as substrate for cyclooxygenase and lipoxygenase, producing less inflammatory eicosanoids. Anti-inflammatory and membrane-stabilizing effects.
Used for inflammatory conditions (skin disease, arthritis, CKD, cardiac disease). Very safe. May cause GI upset at high doses. Marine-sourced preferred over plant (flaxseed).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Omega-3 Fatty Acids dose ranges in dogs, with cited source references: PO 50–100 mg/kg EPA+DHA q24h with food; PO 40–100 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Omega-3 Fatty Acids in dogs: PO.
Cited course lengths for Omega-3 Fatty Acids in dogs include: Long-term daily supplementation; 4-6 weeks for noticeable effect; Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Omega-3 Fatty Acids is indicated in dogs for: Anti-inflammatory (skin, joints, renal, cardiac), Atopic dermatitis, OA, CKD (anti-inflammatory).
These are general warnings for Omega-3 Fatty Acids across species; consult the dog dosing table above for species-specific guidance. Used for inflammatory conditions (skin disease, arthritis, CKD, cardiac disease). Very safe. May cause GI upset at high doses. Marine-sourced preferred over plant (flaxseed).
Why a species-specific page? Omega-3 Fatty Acids pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.