Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Methylprednisolone Acetate Injectable is dosed at 1 mg/kg IM Once; may repeat in 2-6 weeks if needed in dogs, per Papich, Saunders Handbook of Veterinary Drugs 4th ed, printed p.519 (corpus 547), Methylprednisolone, Small Animal Dosage, Dogs - the only retrieved page printing a canine mg/kg IM acetate dose; plumb printed p.865 (corpus 892) for the mg/dog label range. Methylprednisolone Acetate Injectable is used in dogs for Anti-inflammatory depot injection. Routes documented in dogs: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Methylprednisolone Acetate Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Depo-Medrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1 mg/kg | Once; may repeat in 2-6 weeks if needed | Single injection; effect lasts 2-6 weeks | Anti-inflammatory depot injection | Strong | Papich, Saunders Handbook of Veterinary Drugs 4th ed, printed p.519 (corpus 547), Methylprednisolone, Small Animal Dosage, Dogs - the only retrieved page printing a canine mg/kg IM acetate dose; plumb printed p.865 (corpus 892) for the mg/dog label range |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 20–40 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone acetate: 1 mg/kg (or 20-40 mg/dog) IM q1-3wk. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.2–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | ylprednisolone acetate depot injection) q1-3wk or 0.2-0.5 mg/kg p.o. q12h. • Hypoadrenocorticism (acute crisis): 1 mg/kg i.v. once daily until |
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Depot formulation providing prolonged glucocorticoid effect lasting 2-6 weeks. Suppresses inflammation and immune-mediated conditions.
Prolonged adrenal suppression. Cannot titrate dose once injected. Risk of iatrogenic Cushing's with repeated use. Diabetogenic in cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Methylprednisolone Acetate Injectable dose range in dogs, with cited source references: IM 1 mg/kg Once; may repeat in 2-6 weeks if needed. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Methylprednisolone Acetate Injectable in dogs: IM.
Cited course lengths for Methylprednisolone Acetate Injectable in dogs include: Single injection; effect lasts 2-6 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Methylprednisolone Acetate Injectable is indicated in dogs for: Anti-inflammatory depot injection.
These are general warnings for Methylprednisolone Acetate Injectable across species; consult the dog dosing table above for species-specific guidance. Prolonged adrenal suppression. Cannot titrate dose once injected. Risk of iatrogenic Cushing's with repeated use. Diabetogenic in cats.
Why a species-specific page? Methylprednisolone Acetate Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 |
| IV |
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 |
| .5 mg/kg p.o. q12h. • Hypoadrenocorticism (acute crisis): 1 mg/kg i.v. once daily until oral supplementation started. |
| 1–3 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | 1-3 mg/kg p.o. q12h reducing to 1-2 mg/ kg p.o. q48h |
| 1.1 | IM | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | initially 1.1 mg/kg i.m. (methylprednisolone acetate depot injection) q1-3wk or 0.2-0.5 mg/kg p.o. |
| 1 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone acetate: 1 mg/kg (or 20-40 mg/dog) IM q1-3wk. |
| 30 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone sodium succinate (for emergency use): 30 mg/kg IV and |
| 15 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | repeat at 15 mg/kg in 2-6 hours IV. Replacement or anti-inflammatory therapy: |
| 0.25–0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | use 0.25-0.5 mg/kg/day. |
| 0.22–0.44 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone: 0.22-0.44 mg/kg q12-24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.