Cat · Felis catus · typical adult weight 2.50–7.00 kg
Methylprednisolone Acetate Injectable is dosed at 2–5 mg/kg IM Once; may repeat q4-8 weeks if needed in cats, per BSAVA Small Animal Formulary 10th Ed, Part A - Canine and Feline, p.260 (corpus PDF p.276), Methylprednisolone, DOSES, Cats — 1-2 mg/kg i.m. depot q1-3wk (asthma) and 5 mg/kg i.m. depot (inflammation/flea allergy); q4-8 week interval printed verbatim in Veterinary Pharmacology & Therapeutics Box 48.2 (PDF p.1335); 5.5 mg/kg IM in Muller & Kirk p.147 — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829; Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280 — CEILING: FDA-approved label, methylprednisolone acetate — "The average dose is 10 mg/cat (NOT mg/kg) IM with a range up to 20 mg/cat (NOT mg/kg).". Methylprednisolone Acetate Injectable is used in cats for Allergic dermatitis / asthma / IBD. Routes documented in cats: IM. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Methylprednisolone Acetate Injectable in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Depo-Medrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 2–5 mg/kgmax 20 mg total | Once; may repeat q4-8 weeks if needed | Single injection; effect 2-6 weeks | Allergic dermatitis / asthma / IBD | Weak | BSAVA Small Animal Formulary 10th Ed, Part A - Canine and Feline, p.260 (corpus PDF p.276), Methylprednisolone, DOSES, Cats — 1-2 mg/kg i.m. depot q1-3wk (asthma) and 5 mg/kg i.m. depot (inflammation/flea allergy); q4-8 week interval printed verbatim in Veterinary Pharmacology & Therapeutics Box 48.2 (PDF p.1335); 5.5 mg/kg IM in Muller & Kirk p.147 — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829; Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280 — CEILING: FDA-approved label, methylprednisolone acetate — "The average dose is 10 mg/cat (NOT mg/kg) IM with a range up to 20 mg/cat (NOT mg/kg)." |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 10–20 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone acetate: 10-20 mg/cat IM q1-3wk. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5 | IM | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | epot injection) i.m. q1-3wk. • Inflammation/flea allergy: 5 mg/kg i.m. (depot injection) every 2 months or 1 mg/kg p.o. q24h reducing to 2-5 mg/c |
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Depot formulation providing prolonged glucocorticoid effect lasting 2-6 weeks. Suppresses inflammation and immune-mediated conditions.
Prolonged adrenal suppression. Cannot titrate dose once injected. Risk of iatrogenic Cushing's with repeated use. Diabetogenic in cats.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Methylprednisolone Acetate Injectable dose range in cats, with cited source references: IM 2–5 mg/kg Once; may repeat q4-8 weeks if needed. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Methylprednisolone Acetate Injectable in cats: IM.
Cited course lengths for Methylprednisolone Acetate Injectable in cats include: Single injection; effect 2-6 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Methylprednisolone Acetate Injectable is indicated in cats for: Allergic dermatitis / asthma / IBD.
These are general warnings for Methylprednisolone Acetate Injectable across species; consult the cat dosing table above for species-specific guidance. Prolonged adrenal suppression. Cannot titrate dose once injected. Risk of iatrogenic Cushing's with repeated use. Diabetogenic in cats.
Why a species-specific page? Methylprednisolone Acetate Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 |
| PO |
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 |
| 5 mg/kg i.m. (depot injection) every 2 months or 1 mg/kg p.o. q24h reducing to 2-5 mg/cat p.o. q48h. Methylthioninium chloride (Methylene |
| 1–2 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | 1-2 mg/kg (depot injection) i.m. q1-3wk. • Inflammation/flea allergy: 5 mg/kg i.m. (depot injecti |
| 30 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone sodium succinate (for emergency use): 30 mg/kg IV and |
| 15 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | repeat at 15 mg/kg in 2-6 hours IV. Replacement or anti-inflammatory therapy: |
| 0.25–0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | use 0.25-0.5 mg/kg/day. |
| 0.22–0.44 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone: 0.22-0.44 mg/kg q12-24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.