Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Levothyroxine is dosed at 0.02 mg/kg PO q12h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.777 (2026-08-01).. Levothyroxine is used in dogs for Hypothyroidism. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Levothyroxine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Soloxine, Thyro-Tabs
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.02 mg/kg | q12h | Long-term (lifelong) | Hypothyroidism | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.777 (2026-08-01). |
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Synthetic T4 (thyroxine) that is converted to active T3 in peripheral tissues. Restores normal metabolic rate, thermogenesis, and organ function.
Dose based on body weight, adjusted by monitoring serum T4 levels (4-6 hour post-pill sample). Give on empty stomach. Monitor for signs of thyrotoxicosis (tachycardia, panting, anxiety). Dogs primarily.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Levothyroxine dose range in dogs, with cited source references: PO 0.02 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Levothyroxine in dogs: PO.
Cited course lengths for Levothyroxine in dogs include: Long-term (lifelong). Duration depends on the indication — match it to the specific dose rule in the table above.
Levothyroxine is indicated in dogs for: Hypothyroidism.
These are general warnings for Levothyroxine across species; consult the dog dosing table above for species-specific guidance. Dose based on body weight, adjusted by monitoring serum T4 levels (4-6 hour post-pill sample). Give on empty stomach. Monitor for signs of thyrotoxicosis (tachycardia, panting, anxiety). Dogs primarily.
Why a species-specific page? Levothyroxine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.