Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sodium Nitrite is used in dog for Cyanide poisoning (non-smoke inhalation). Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Sodium Nitrite in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Nithiodote
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 10–20 mg/kg | Single slow IV dose | Single dose; always follow with sodium thiosulfate; may repeat at 50% dose once | Cyanide poisoning (non-smoke inhalation) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; ASPCA Toxicology |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Oxidizes hemoglobin to methemoglobin, which has high affinity for cyanide, forming cyanmethemoglobin and freeing cytochrome oxidase. Combined with sodium thiosulfate.
Creates controlled methemoglobinemia — dangerous if overdosed. Monitor methemoglobin levels. Do not use in smoke inhalation (already elevated carboxyhemoglobin).
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Sodium Nitrite pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.