Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sodium Nitrite is dosed at 10–20 mg/kg IV Single slow IV dose in dogs, per Hoareau G. Smoke inhalation. Presented at: Pacific Veterinary Conferences; 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1193 (2026-08-01).. Sodium Nitrite is used in dogs for Cyanide poisoning (non-smoke inhalation). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Sodium Nitrite in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nithiodote
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 10–20 mg/kg | Single slow IV dose | Single dose; always follow with sodium thiosulfate; may repeat at 50% dose once | Cyanide poisoning (non-smoke inhalation) | Moderate | Hoareau G. Smoke inhalation. Presented at: Pacific Veterinary Conferences; 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1193 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Oxidizes hemoglobin to methemoglobin, which has high affinity for cyanide, forming cyanmethemoglobin and freeing cytochrome oxidase. Combined with sodium thiosulfate.
Creates controlled methemoglobinemia — dangerous if overdosed. Monitor methemoglobin levels. Do not use in smoke inhalation (already elevated carboxyhemoglobin).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sodium Nitrite dose range in dogs, with cited source references: IV 10–20 mg/kg Single slow IV dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sodium Nitrite in dogs: IV.
Cited course lengths for Sodium Nitrite in dogs include: Single dose; always follow with sodium thiosulfate; may repeat at 50% dose once. Duration depends on the indication — match it to the specific dose rule in the table above.
Sodium Nitrite is indicated in dogs for: Cyanide poisoning (non-smoke inhalation).
These are general warnings for Sodium Nitrite across species; consult the dog dosing table above for species-specific guidance. Creates controlled methemoglobinemia — dangerous if overdosed. Monitor methemoglobin levels. Do not use in smoke inhalation (already elevated carboxyhemoglobin).
Why a species-specific page? Sodium Nitrite pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.