Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pantoprazole is dosed at 0.7–1 mg/kg IV q12-24h in dogs, per Kuhl A, Odunayo A, Price J, et al. Comparative analysis of the effect of IV administered acid suppressants on gastric pH in dogs. J Vet Intern Med. 2020;34(2):678-683. doi:10.1111/jvim.15718 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1011 (2026-08-01). — Plumb's 10th ed (held) printed p.984, Pantoprazole monograph spanning p.983-984; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Pantoprazole is used in dogs for Acute GI bleeding. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pantoprazole in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Protonix
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.7–1 mg/kg | q12-24h | Until oral PPI tolerated | Acute GI bleeding | Moderate | Kuhl A, Odunayo A, Price J, et al. Comparative analysis of the effect of IV administered acid suppressants on gastric pH in dogs. J Vet Intern Med. 2020;34(2):678-683. doi:10.1111/jvim.15718 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1011 (2026-08-01). — Plumb's 10th ed (held) printed p.984, Pantoprazole monograph spanning p.983-984; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | dextrose 5% injection, sodium chloride 0.9% injection, or Ringer’s lactate injection |
| 5 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | prazole via IV line with dextrose 5% injection, sodium chloride 0.9% injection, or |
| 0.9 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | prazole via IV line with dextrose 5% injection, sodium chloride 0.9% injection, or |
| 0.9 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | dextrose 5% injection, sodium chloride 0.9% injection, or Ringer’s lactate injection |
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Irreversibly inhibits H+/K+ ATPase proton pump. IV formulation particularly useful in critically ill animals unable to take oral medications.
IV form available for hospitalized patients. Fewer drug interactions than omeprazole. Long-term use may affect mineral absorption.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pantoprazole dose range in dogs, with cited source references: IV 0.7–1 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pantoprazole in dogs: IV.
Cited course lengths for Pantoprazole in dogs include: Until oral PPI tolerated. Duration depends on the indication — match it to the specific dose rule in the table above.
Pantoprazole is indicated in dogs for: Acute GI bleeding.
These are general warnings for Pantoprazole across species; consult the dog dosing table above for species-specific guidance. IV form available for hospitalized patients. Fewer drug interactions than omeprazole. Long-term use may affect mineral absorption.
Why a species-specific page? Pantoprazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.7–1 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.318 | 0.7-1.0 mg/kg i.v. over 15 min q24h. Oral dose not established in cats/dogs but likely similar to i.v. |
| 0.5–0.6 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | • 0.5-0.6 mg/kg once daily PO. |
| 0.5–1 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | • Intravenous administration (24 hours): 0.5-1 mg/kg IV infusion over 24 hours. |
| 1 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.636 | approximately 0.4 mg/mL. Administer final dose (1 mg/kg) over 15 minutes. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.