Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tobramycin Systemic is dosed at 2–4 mg/kg IV q8h or 6-10 mg/kg q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1247-1248 (corpus PDF p.1274-1275), Tobramycin, Systemic monograph, Dosages — DOGS & CATS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Tobramycin Ophthalmic monograph]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.1247-1248, Tobramycin, Systemic monograph [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Polymyxin B, Systemic monograph, a different antibiotic]; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Tobramycin Systemic is used in dogs for Serious Pseudomonas and gram-negative infections. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tobramycin Systemic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nebcin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–4 mg/kg | q8h or 6-10 mg/kg q24h |
| 5-7 days |
| Serious Pseudomonas and gram-negative infections |
| Moderate |
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1247-1248 (corpus PDF p.1274-1275), Tobramycin, Systemic monograph, Dosages — DOGS & CATS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Tobramycin Ophthalmic monograph]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.1247-1248, Tobramycin, Systemic monograph [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Polymyxin B, Systemic monograph, a different antibiotic]; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4–6 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.420 | 4-6 mg/kg i.v., s.c., i.m. q24h. For severe infections (including sepsis), doses as high as 12 mg/k |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds 30S ribosomal subunit causing misreading of mRNA. Bactericidal. Particularly effective against Pseudomonas aeruginosa.
Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tobramycin Systemic dose range in dogs, with cited source references: IV 2–4 mg/kg q8h or 6-10 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tobramycin Systemic in dogs: IV.
Cited course lengths for Tobramycin Systemic in dogs include: 5-7 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Tobramycin Systemic is indicated in dogs for: Serious Pseudomonas and gram-negative infections.
These are general warnings for Tobramycin Systemic across species; consult the dog dosing table above for species-specific guidance. Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.
Why a species-specific page? Tobramycin Systemic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.