ExoticRx · exoticrx.com/drugs/tobramycin-systemic
US brand names:Nebcin
Tobramycin Systemic is dosed at 5–10 mg/kg IM q12h in great horned owls, per Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.655. Row as printed binds this dose to raptors on its own line: "Tobramycin Nebcin Injection Raptors IM 5-10 mg/kg bid for 5-7 d Least nephrotoxic of all current". Verify against current literature before clinical use.
Binds 30S ribosomal subunit causing misreading of mRNA. Bactericidal. Particularly effective against Pseudomonas aeruginosa.
Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Great Horned Owl drugsAll Harris Hawk drugsAll Peregrine Falcon drugsAll Red-tailed Hawk drugs
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A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IV | 2–3 mg/kg | q8h or 5-8 mg/kg q24h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1247-1248, Tobramycin, Systemic monograph, Dosages — DOGS & CATS.Compilation only — we have not located an independent source that prints this figure. |
| Dog (Domestic) | IV | 2–4 mg/kg | q8h or 6-10 mg/kg q24h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.1247-1248, Tobramycin, Systemic monograph, Dosages — DOGS & CATS. — Plumb's 10th ed printed p.1247-1248, Tobramycin, Systemic monograph.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.