ExoticRx · exoticrx.com/drugs/tobramycin-ophthalmic
US brand names:Tobrex
Aminoglycoside binding 30S ribosomal subunit. Bactericidal against gram-negatives including Pseudomonas. Important for corneal ulcers.
Less corneal epithelial toxicity than gentamicin with prolonged use. Good Pseudomonas coverage. Can fortify (prepare higher concentration) for severe infections.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Less epithelial toxicity than gentamicin | q4-8h (q1-2h for severe) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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