ExoticRx · exoticrx.com/drugs/tobramycin-ophthalmic
US brand names:Tobrex
Aminoglycoside binding 30S ribosomal subunit. Bactericidal against gram-negatives including Pseudomonas. Important for corneal ulcers.
Less corneal epithelial toxicity than gentamicin with prolonged use. Good Pseudomonas coverage. Can fortify (prepare higher concentration) for severe infections.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Less epithelial toxicity than gentamicin | 4 to 6 times daily, q30-60min if severe | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1406, Tobramycin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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