Cat · Felis catus · typical adult weight 2.50–7.00 kg
Tobramycin Systemic is dosed at 2–3 mg/kg IV q8h or 5-8 mg/kg q24h in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1247-1248 (corpus PDF p.1274-1275), Tobramycin, Systemic monograph, Dosages — DOGS & CATS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Tobramycin Ophthalmic monograph]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Tobramycin Systemic is used in cats for Serious gram-negative infections. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Tobramycin Systemic in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nebcin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–3 mg/kg | q8h or 5-8 mg/kg q24h | 5-7 days | Serious gram-negative infections | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1247-1248 (corpus PDF p.1274-1275), Tobramycin, Systemic monograph, Dosages — DOGS & CATS [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Tobramycin Ophthalmic monograph]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4–6 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.420 | 4-6 mg/kg i.v., s.c., i.m. q24h. For severe infections (including sepsis), doses as high as 12 mg/k |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds 30S ribosomal subunit causing misreading of mRNA. Bactericidal. Particularly effective against Pseudomonas aeruginosa.
Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tobramycin Systemic dose range in cats, with cited source references: IV 2–3 mg/kg q8h or 5-8 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tobramycin Systemic in cats: IV.
Cited course lengths for Tobramycin Systemic in cats include: 5-7 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Tobramycin Systemic is indicated in cats for: Serious gram-negative infections.
These are general warnings for Tobramycin Systemic across species; consult the cat dosing table above for species-specific guidance. Nephrotoxic and ototoxic. Therapeutic drug monitoring essential. Avoid concurrent nephrotoxins. Ensure adequate hydration.
Why a species-specific page? Tobramycin Systemic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.