Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Imidacloprid is dosed at 10 mg/kg TOPICAL q30d in dogs, per ADVANTAGE MULTI FOR DOGS - Imidacloprid, Moxidectin Solution [US Product Label for Dogs]. Elanco US, Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.943 (2026-08-01).. Imidacloprid is used in dogs for Flea control. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Imidacloprid in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Advantage
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 10 mg/kg | q30d | Monthly application | Flea control | Strong | ADVANTAGE MULTI FOR DOGS - Imidacloprid, Moxidectin Solution [US Product Label for Dogs]. Elanco US, Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.943 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds insect nicotinic acetylcholine receptors, causing paralysis and death of fleas. Highly selective for insect receptors over mammalian.
External use only. Very safe in mammals due to receptor selectivity. May cause transient skin irritation at application site. Do not ingest.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Imidacloprid dose range in dogs, with cited source references: TOPICAL 10 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Imidacloprid in dogs: TOPICAL.
Cited course lengths for Imidacloprid in dogs include: Monthly application. Duration depends on the indication — match it to the specific dose rule in the table above.
Imidacloprid is indicated in dogs for: Flea control.
These are general warnings for Imidacloprid across species; consult the dog dosing table above for species-specific guidance. External use only. Very safe in mammals due to receptor selectivity. May cause transient skin irritation at application site. Do not ingest.
Why a species-specific page? Imidacloprid pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.