ExoticRx · exoticrx.com/drugs/imidacloprid
US brand names:Advantage
Imidacloprid is dosed at 10 mg/kg TOPICAL q30d in rabbits, per Hutchinson MJ, Jacobs DE, Bell GD, et al. Evaluation of imidacloprid for the treatment and prevention of cat flea (Ctenocephalides felis felis) infestations on rabbits. Vet Rec. 2001;148:695-696. doi:10.1136/vr.148.22.695; Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.850 (2026-08-01).. Verify against current literature before clinical use.
Binds insect nicotinic acetylcholine receptors, causing paralysis and death of fleas. Highly selective for insect receptors over mammalian.
External use only. Very safe in mammals due to receptor selectivity. May cause transient skin irritation at application site. Do not ingest.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Rabbit (Domestic) drugsAll Sugar Glider drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | TOPICAL | 10 mg/kg | q30d | Strong | Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.219 (2026-08-01). |
| Dog (Domestic) | TOPICAL | 10 mg/kg | q30d | Strong | ADVANTAGE MULTI FOR DOGS - Imidacloprid, Moxidectin Solution [US Product Label for Dogs]. Elanco US, Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.943 (2026-08-01). |
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