Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Voriconazole is dosed at 3–4 mg/kg PO q12h in dogs, per Graupmann-Kuzma A, Valentine BA, Shubitz LF, Dial SM, Watrous B, Tornquist SJ. Coccidioidomycosis in dogs and cats: A review. J Am Anim Hosp Assoc. 2008;44:226-235. doi:10.5326/0440226 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1343 (2026-08-01). — Plumb's 10th ed (held) printed p.1314, Voriconazole monograph spanning p.1314-1316; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 14 — "3), 2.5 - 3.3 mg/kg Storage/Stability PO every 12 hours14" — which resolves in the monograph's own reference list to: Bray RN, Raghu CL, Leuin AS, Barry-Heffernan CA, Pritchard JC. Oral administration of voriconazole with surgical fungal plaque debridement for the treatment of sinonasal aspergillosis with cribriform plate lysis in three dogs. J Am Vet Med Assoc. 2020;256(1):111-116. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.. Voriconazole is used in dogs for Aspergillosis (nasal and disseminated). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Voriconazole in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vfend
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 3–4 mg/kg | q12h | Long-term (months) | Aspergillosis (nasal and disseminated) | Moderate | Graupmann-Kuzma A, Valentine BA, Shubitz LF, Dial SM, Watrous B, Tornquist SJ. Coccidioidomycosis in dogs and cats: A review. J Am Anim Hosp Assoc. 2008;44:226-235. doi:10.5326/0440226 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1343 (2026-08-01). — Plumb's 10th ed (held) printed p.1314, Voriconazole monograph spanning p.1314-1316; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 14 — "3), 2.5 - 3.3 mg/kg Storage/Stability PO every 12 hours14" — which resolves in the monograph's own reference list to: Bray RN, Raghu CL, Leuin AS, Barry-Heffernan CA, Pritchard JC. Oral administration of voriconazole with surgical fungal plaque debridement for the treatment of sinonasal aspergillosis with cribriform plate lysis in three dogs. J Am Vet Med Assoc. 2020;256(1):111-116. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5–6 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.875 | • 5-6 mg/kg q12h PO. (Safety of repeated doses in dogs has not been examined.) |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.
Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Voriconazole dose range in dogs, with cited source references: PO 3–4 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Voriconazole in dogs: PO.
Cited course lengths for Voriconazole in dogs include: Long-term (months). Duration depends on the indication — match it to the specific dose rule in the table above.
Voriconazole is indicated in dogs for: Aspergillosis (nasal and disseminated).
These are general warnings for Voriconazole across species; consult the dog dosing table above for species-specific guidance. Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Why a species-specific page? Voriconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.