ExoticRx · exoticrx.com/drugs/voriconazole
US brand names:Vfend
Voriconazole is dosed at 10 mg/kg PO q24h x 47 days in bearded dragons, per 474. Van Waeyenberghe L, Baert K, Pasmans F, et al. Voriconazole, a safe alternative for treating infections caused by the Chrysosporium anamorph of Nannizziopsis vriesii in bearded dragons (Pogona vitticeps). Med Mycol. 2010;48:880-885. / 427. Sim RR. Voriconazole. J Exot Pet Med. 2016;25:342- — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.223 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — CORROBORATED 2026-08-06 by independent literature: Voriconazole, a safe alternative for treating infections caused by the Chrysosporium anamorph of Nannizziopsis vriesii in bearded dragons (Pogona vitticeps). (Medical mycology, 2010). doi:10.3109/13693781003743122. https://doi.org/10.3109/13693781003743122. The paper reports this drug at this dose in this species: "urteen naturally-infected bearded dragons (Pogona vitticeps), from the same owner, were treated […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, . Verify against current literature before clinical use.
Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.
Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Species references:All Amazon Parrot drugsAll Bearded Dragon drugsAll Chicken (Poultry) drugsAll Dog (Domestic) drugsAll Domestic Pigeon drugsAll Guinea Pig drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 9 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–4 mg/kg | q12h | Moderate | Graupmann-Kuzma A, Valentine BA, Shubitz LF, Dial SM, Watrous B, Tornquist SJ. Coccidioidomycosis in dogs and cats: A review. J Am Anim Hosp Assoc. 2008;44:226-235. doi:10.5326/0440226 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1343 (2026-08-01). — Plumb's 10th ed (held) printed p.1314, Voriconazole monograph spanning p.1314-1316; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 14 — "3), 2.5 - 3.3 mg/kg Storage/Stability PO every 12 hours14" — which resolves in the monograph's own reference list to: Bray RN, Raghu CL, Leuin AS, Barry-Heffernan CA, Pritchard JC. Oral administration of voriconazole with surgical fungal plaque debridement for the treatment of sinonasal aspergillosis with cribriform plate lysis in three dogs. J Am Vet Med Assoc. 2020;256(1):111-116. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.