Which species have cited Voriconazole dosing data?

Voriconazole dosing in the ExoticRx formulary covers 9 species: Amazon Parrot, Bearded Dragon, Chicken (Poultry), Dog (Domestic), Domestic Pigeon, Guinea Pig, Peregrine Falcon, Red-tailed Hawk, Russian Tortoise.

Is Voriconazole a controlled substance?

Voriconazole is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

How does Voriconazole work?

Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.

Voriconazole

US brand names:Vfend

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Voriconazole is dosed at 10 mg/kg PO q24h in guinea pigs, per Chandrasekar P, Cutright J, Manavathu E. Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model. J Antimicrob Chemother. 2000;45:673-676. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.774 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a). Verify against current literature before clinical use.

Drug Class

Antifungal

Routes

POIV

Indications

AspergillosisAspergillosis (nasal and disseminated)Fungal infections

Side effects & warnings

Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.

Sample dosing (1 of 9 cited rules)

A dog/cat sample is shown here. Cited dosing for all 9 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	3–4 mg/kg	q12h	Moderate	Graupmann-Kuzma A, Valentine BA, Shubitz LF, Dial SM, Watrous B, Tornquist SJ. Coccidioidomycosis in dogs and cats: A review. J Am Anim Hosp Assoc. 2008;44:226-235. doi:10.5326/0440226 — Plumb's 10th ed printed p.1314, Voriconazole monograph spanning p.1314-1316. \| ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 14 — "3), 2.5 - 3.3 mg/kg Storage/Stability PO every 12 hours14" — which resolves in the monograph's own reference list to: Bray RN, Raghu CL, Leuin AS, Barry-Heffernan CA, Pritchard JC. Oral administration of voriconazole with surgical fungal plaque debridement for the treatment of sinonasal aspergillosis with cribriform plate lysis in three dogs. J Am Vet Med Assoc. 2020;256(1):111-116. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.

Backed by 9 published sourcesShow

· 474. Van Waeyenberghe L, Baert K, Pasmans F, et al. Voriconazole, a safe alternative for treating infections caused by the Chrysosporium anamorph of Nannizziopsis vriesii in bearded dragons (Pogona vitticeps). Med Mycol. 2010;48:880-885. / 427. Sim RR. Voriconazole. J Exot Pet Med. 2016;25:342- — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.223 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). — CORROBORATED 2026-08-06 by independent literature: Voriconazole, a safe alternative for treating infections caused by the Chrysosporium anamorph of Nannizziopsis vriesii in bearded dragons (Pogona vitticeps). (Medical mycology, 2010). doi:10.3109/13693781003743122. https://doi.org/10.3109/13693781003743122. The paper reports this drug at this dose in this species: "urteen naturally-infected bearded dragons (Pogona vitticeps), from the same owner, were treated […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct.

Upgrade for Full Details

Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.

View Plans

819. Sanchez-Migallon Guzman D, Flammer K, Papich MG, et al. Pharmacokinetics of voriconazole after oral administration of single and multiple doses in Hispaniolan Amazon parrots (Amazona ventralis). Am J Vet Res. 2010;71:460-467. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.428 doi:10.2460/ajvr.71.4.460 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.2 (Antifungal Agents Used in Birds).

· 82. Beernaert LA, Baert K, Marin P, et al. Designing voriconazole treatment for racing pigeons: balancing between hepatic enzyme auto induction and toxicity. Med Mycol. 2009;47:276-285. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.428 doi:10.1080/13693780802262115 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.2 (Antifungal Agents Used in Birds).

· Burhenne J, Haefeli WE, Hess M, et al. Pharmacokinetics, tissue concentrations, and safety of the antifungal agent voriconazole in chickens. J Avian Med Surg. 2008;22:199-220. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.632 doi:10.1647/2007-003.1 — Carpenter's Exotic Animal Formulary 6th ed, Table 6.2 (Antifungal Agents Used in Backyard Poultry, Gamebirds, and Waterfowl).

· Chandrasekar P, Cutright J, Manavathu E. Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model. J Antimicrob Chemother. 2000;45:673-676. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.774 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).

· Graupmann-Kuzma A, Valentine BA, Shubitz LF, Dial SM, Watrous B, Tornquist SJ. Coccidioidomycosis in dogs and cats: A review. J Am Anim Hosp Assoc. 2008;44:226-235. doi:10.5326/0440226 — Plumb's 10th ed printed p.1314, Voriconazole monograph spanning p.1314-1316. | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 14 — "3), 2.5 - 3.3 mg/kg Storage/Stability PO every 12 hours14" — which resolves in the monograph's own reference list to: Bray RN, Raghu CL, Leuin AS, Barry-Heffernan CA, Pritchard JC. Oral administration of voriconazole with surgical fungal plaque debridement for the treatment of sinonasal aspergillosis with cribriform plate lysis in three dogs. J Am Vet Med Assoc. 2020;256(1):111-116. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.

· PRIMARY LITERATURE, species group includes this species: Azmanis P, Pappalardo L, Sara ZAJ, Silvanose C, Naidoo V. "Pharmacokinetics of voriconazole after a single intramuscular injection in large falcons (Falco spp.)." Med Mycol 2020;58(5):661-666. doi:10.1093/mmy/myz102. PMID 31608415 - https://pubmed.ncbi.nlm.nih.gov/31608415/. Abstract retrieved and read 2026-08-20. Study covered gyrfalcons, saker falcons and peregrine falcons. Full text not read.

· PRIMARY LITERATURE, species-specific: Gentry J, Montgerard C, Crandall E, Cruz-Espindola C, Boothe D, Bellah J. "Voriconazole Disposition After Single and Multiple, Oral Doses in Healthy, Adult Red-tailed Hawks (Buteo jamaicensis)." J Avian Med Surg 2014;28(3):201-208. doi:10.1647/20-077. PMID 25843319 - https://pubmed.ncbi.nlm.nih.gov/25843319/. Abstract retrieved and read 2026-08-20; the dose, interval, duration and safety outcome above are stated in it. Full text not read.

Voriconazole

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Voriconazole dosing data (9 dose rules)

Evidence levels across 9 dose rules

Sample dosing (1 of 9 cited rules)

Upgrade for Full Details

Other formulations of Voriconazole

Voriconazole

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Voriconazole dosing data (9 dose rules)

Evidence levels across 9 dose rules

Sample dosing (1 of 9 cited rules)

Upgrade for Full Details

Other formulations of Voriconazole

Articles mentioning Voriconazole

More Antifungal drugs