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Voriconazole for Amazon Parrots

Bird · Amazona spp. · typical adult weight 0.35–0.55 kg

Voriconazole is dosed at 12–24 mg/kg PO single dose in amazon parrots, per Guzman DS, Flammer K, Papich MG, Grooters AM, Shaw S, Applegate J, Tully TN. Pharmacokinetics of voriconazole after oral administration of single and multiple doses in Hispaniolan Amazon parrots (Amazona ventralis). Am J Vet Res. 2010 Apr;71(4):460-467. doi:10.2460/ajvr.71.4.460. PMID 20367055. URL: https://pubmed.ncbi.nlm.nih.gov/20367055/. Voriconazole (Antifungal) has cited veterinary dosing for amazon parrots. Routes documented in amazon parrots: PO. A typical adult amazon parrot weighs 0.35–0.55 kg. ExoticRx lists 2 cited dose rules for Voriconazole in amazon parrots, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Vfend

Dose ranges

RouteDoseFrequencyIndicationEvidenceSource
PO12–24 mg/kgsingle doseWeakGuzman DS, Flammer K, Papich MG, Grooters AM, Shaw S, Applegate J, Tully TN. Pharmacokinetics of voriconazole after oral administration of single and multiple doses in Hispaniolan Amazon parrots (Amazona ventralis). Am J Vet Res. 2010 Apr;71(4):460-467. doi:10.2460/ajvr.71.4.460. PMID 20367055. URL: https://pubmed.ncbi.nlm.nih.gov/20367055/
PO18 mg/kgevery 8 hours (for 11 days)WeakGuzman DS, Flammer K, Papich MG, Grooters AM, Shaw S, Applegate J, Tully TN. Pharmacokinetics of voriconazole after oral administration of single and multiple doses in Hispaniolan Amazon parrots (Amazona ventralis). Am J Vet Res. 2010 Apr;71(4):460-467. doi:10.2460/ajvr.71.4.460. PMID 20367055. URL: https://pubmed.ncbi.nlm.nih.gov/20367055/

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Mechanism of action

Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.

Side effects & warnings

Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.

Species-specific contraindications and adverse-reaction reports for amazon parrots may differ from canine / feline reference data — consult the primary citations listed with each rule.

Frequently asked questions

What is the dose of Voriconazole for Amazon Parrots?

Voriconazole dose ranges in amazon parrots, with cited source references: PO 12–24 mg/kg single dose; PO 18 mg/kg every 8 hours (for 11 days).

How is Voriconazole administered in Amazon Parrots?

Documented routes for Voriconazole in amazon parrots: PO.

What are the side effects of Voriconazole in Amazon Parrots?

These are general warnings for Voriconazole across species; consult the amazon parrot dosing table above for species-specific guidance. Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.

Voriconazole dosing in other species

Why a species-specific page? Voriconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in amazon parrots — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.