Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Voriconazole is dosed at 10 mg/kg PO q24h in guinea pigs, per Chandrasekar P, Cutright J, Manavathu E. Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model. J Antimicrob Chemother. 2000;45:673-676. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.774 (2026-08-01, PENDING REVIEW). Voriconazole is used in guinea pigs for Invasive aspergillosis (antifungal). Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Voriconazole in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vfend
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 10 mg/kg | q24h | Invasive aspergillosis (antifungal) | Weak | Chandrasekar P, Cutright J, Manavathu E. Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model. J Antimicrob Chemother. 2000;45:673-676. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.774 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.
Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Voriconazole dose range in guinea pigs, with cited source references: PO 10 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Voriconazole in guinea pigs: PO.
Voriconazole is indicated in guinea pigs for: Invasive aspergillosis (antifungal).
These are general warnings for Voriconazole across species; consult the guinea pig dosing table above for species-specific guidance. Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Why a species-specific page? Voriconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.