Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Enalapril is dosed at 0.5 mg/kg PO q12-24h in dogs, per Enacard Tablets for Dogs [UK Datasheet]. Merial Limited; 2006. | Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33(3):1127-1140. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.474 (2026-08-01). — Plumb's 10th ed (held) printed p.447, Enalapril monograph spanning p.445-447; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Enalapril is used in dogs for Congestive heart failure, proteinuria. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Enalapril in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Enacard, Vasotec
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5 mg/kg | q12-24h | Long-term | Congestive heart failure, proteinuria |
| Enacard Tablets for Dogs [UK Datasheet]. Merial Limited; 2006. | Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33(3):1127-1140. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.474 (2026-08-01). — Plumb's 10th ed (held) printed p.447, Enalapril monograph spanning p.445-447; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.162 | 0.5 mg/kg p.o. q24h increasing to 0.5 mg/kg p.o. q12h after 2 weeks in the absence of a clinical response. |
| 0.25–1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.162 | 0.25-1 mg/kg p.o. q12-24h. |
| 3 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.162 | Can be up-titrated slowly to effect. Doses up to 3 mg/kg have been used |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Prodrug converted to enalaprilat, which inhibits ACE. Reduces angiotensin II, decreases aldosterone, reduces preload and afterload.
Monitor renal function (BUN/creatinine) and electrolytes. Hypotension with concurrent diuretics. Primarily renal elimination (prefer benazepril in renal disease). CONTRAINDICATED in pregnancy.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Enalapril dose range in dogs, with cited source references: PO 0.5 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Enalapril in dogs: PO.
Cited course lengths for Enalapril in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Enalapril is indicated in dogs for: Congestive heart failure, proteinuria.
These are general warnings for Enalapril across species; consult the dog dosing table above for species-specific guidance. Monitor renal function (BUN/creatinine) and electrolytes. Hypotension with concurrent diuretics. Primarily renal elimination (prefer benazepril in renal disease). CONTRAINDICATED in pregnancy.
Why a species-specific page? Enalapril pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.