Cat · Felis catus · typical adult weight 2.50–7.00 kg
Enalapril is dosed at 0.25–0.5 mg/kg PO q12-24h in cats, per Treatment Recommendations for CKD in Dogs. International Renal Interest Society; 2019. | Polzin DJ. Evidence-based step-wise approach to managing chronic kidney disease in dogs and cats. J Vet Emerg Crit Care. 2013;23(2):205-215. | Bartges JW. Chronic kidney disease in dogs and cats. Vet Clin North Am Small Animal Pract. 2012;42(4):669-692. | Littman MP. Protein-losing nephropathy in small animals. Vet Clin North Am Small Animal Pract. 2011;41(1):31-62. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.474 (2026-08-01).. Enalapril is used in cats for Heart failure, proteinuria. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Enalapril in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Enacard, Vasotec
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.25–0.5 mg/kg | q12-24h | Long-term | Heart failure, proteinuria | Moderate | Treatment Recommendations for CKD in Dogs. International Renal Interest Society; 2019. | Polzin DJ. Evidence-based step-wise approach to managing chronic kidney disease in dogs and cats. J Vet Emerg Crit Care. 2013;23(2):205-215. | Bartges JW. Chronic kidney disease in dogs and cats. Vet Clin North Am Small Animal Pract. 2012;42(4):669-692. | Littman MP. Protein-losing nephropathy in small animals. Vet Clin North Am Small Animal Pract. 2011;41(1):31-62. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.474 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Prodrug converted to enalaprilat, which inhibits ACE. Reduces angiotensin II, decreases aldosterone, reduces preload and afterload.
Monitor renal function (BUN/creatinine) and electrolytes. Hypotension with concurrent diuretics. Primarily renal elimination (prefer benazepril in renal disease). CONTRAINDICATED in pregnancy.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Enalapril dose range in cats, with cited source references: PO 0.25–0.5 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Enalapril in cats: PO.
Cited course lengths for Enalapril in cats include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Enalapril is indicated in cats for: Heart failure, proteinuria.
These are general warnings for Enalapril across species; consult the cat dosing table above for species-specific guidance. Monitor renal function (BUN/creatinine) and electrolytes. Hypotension with concurrent diuretics. Primarily renal elimination (prefer benazepril in renal disease). CONTRAINDICATED in pregnancy.
Why a species-specific page? Enalapril pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.