Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sulfasalazine is used in dog for Colitis, Inflammatory bowel disease / colitis. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Sulfasalazine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Azulfidine
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–30 mg/kg | q8-12h | 4-6 weeks then taper | Colitis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 20–50 mg/kg | q8-12h | Initial 4 weeks, then taper | Inflammatory bowel disease / colitis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Absolute dose ceiling, regardless of body weight: 3000 mg total (PO).
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Cleaved by colonic bacteria to 5-aminosalicylic acid (mesalamine) and sulfapyridine. 5-ASA acts locally to reduce colonic inflammation.
Used for colitis in dogs. KCS (dry eye) risk — monitor Schirmer tear test. Cats: salicylate sensitivity. Folate supplementation recommended. GI upset.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Sulfasalazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.