Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Paroxetine is dosed at 0.5–2 mg/kg PO q24h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1016 (2026-08-01).. Paroxetine is used in dogs for Anxiety disorders, compulsive behaviors. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Paroxetine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Paxil
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q24h | Weeks to months | Anxiety disorders, compulsive behaviors | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1016 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective serotonin reuptake inhibitor. Also has mild anticholinergic activity contributing to anxiolytic effects.
Used for anxiety disorders, aggression, and compulsive behaviors. 4-6 weeks for full effect. Serotonin syndrome risk. GI upset initially. Do not combine with MAO inhibitors.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Paroxetine dose range in dogs, with cited source references: PO 0.5–2 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Paroxetine in dogs: PO.
Cited course lengths for Paroxetine in dogs include: Weeks to months. Duration depends on the indication — match it to the specific dose rule in the table above.
Paroxetine is indicated in dogs for: Anxiety disorders, compulsive behaviors.
These are general warnings for Paroxetine across species; consult the dog dosing table above for species-specific guidance. Used for anxiety disorders, aggression, and compulsive behaviors. 4-6 weeks for full effect. Serotonin syndrome risk. GI upset initially. Do not combine with MAO inhibitors.
Why a species-specific page? Paroxetine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.