ExoticRx · exoticrx.com/drugs/paroxetine
US brand names:Paxil
Paroxetine is dosed at 0.5–2 mg/kg PO q24h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1016 (2026-08-01).. Verify against current literature before clinical use.
Selective serotonin reuptake inhibitor. Also has mild anticholinergic activity contributing to anxiolytic effects.
Used for anxiety disorders, aggression, and compulsive behaviors. 4-6 weeks for full effect. Serotonin syndrome risk. GI upset initially. Do not combine with MAO inhibitors.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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