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Aripiprazole

Abilify

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Behavioral

Routes

PO

Indications

Feather-destructive behaviorRefractory compulsive disorder

Mechanism of Action

Partial agonist at dopamine D2 and serotonin 5-HT1A receptors. Antagonist at 5-HT2A. Stabilizes dopaminergic activity without full blockade.

Side effects & warnings

Less sedating than other antipsychotics. May cause restlessness (akathisia). Limited veterinary data — investigational for refractory behavioral conditions in parrots.

Species with Aripiprazole dosing data (2 dose rules)

Species references:All African Grey Parrot drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · Crowell-Davis SL, Veterinary Psychopharmacology, 2nd Ed
  • · Seibert LM, Psittacine behavioral pharmacology review

Sample dosing (1 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO0.1–0.5 mg/kgq24hAnecdotalCrowell-Davis SL, Veterinary Psychopharmacology, 2nd Ed

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