Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenylephrine Ophthalmic is used in dog for Mydriasis without cycloplegia, conjunctival decongestion. Routes documented in dog: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenylephrine Ophthalmic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Mydfrin, Neo-Synephrine Ophthalmic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | 0 1 drop 2.5% per eye | PRN for exam or q6-8h therapeutic | Single dose for exam; short-term therapeutic | Mydriasis without cycloplegia, conjunctival decongestion | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Alpha-1 adrenergic agonist causing contraction of iris dilator muscle (mydriasis) without cycloplegia. Also causes conjunctival vasoconstriction.
10% concentration can cause systemic hypertension — use 2.5% in small animals. Mydriasis without cycloplegia (pupil still accommodates). Avoid in narrow-angle glaucoma.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Phenylephrine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.