Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenylephrine Ophthalmic is used in dogs for Mydriasis without cycloplegia, conjunctival decongestion. Routes documented in dogs: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenylephrine Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mydfrin, Neo-Synephrine Ophthalmic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | See the cited source for the printed regimen | PRN for exam or q6-8h therapeutic | Single dose for exam; short-term therapeutic | Mydriasis without cycloplegia, conjunctival decongestion | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1393, Phenylephrine Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
| 3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • CRI: 10 mcg/kg (0.01 mg/kg) IV, followed by 3 mcg/kg/min IV. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.01 |
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Alpha-1 adrenergic agonist causing contraction of iris dilator muscle (mydriasis) without cycloplegia. Also causes conjunctival vasoconstriction.
10% concentration can cause systemic hypertension — use 2.5% in small animals. Mydriasis without cycloplegia (pupil still accommodates). Avoid in narrow-angle glaucoma.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenylephrine Ophthalmic dose range in dogs, with cited source references: TOPICAL (ophthalmic) See the cited source for the printed regimen PRN for exam or q6-8h therapeutic. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenylephrine Ophthalmic in dogs: TOPICAL (ophthalmic).
Cited course lengths for Phenylephrine Ophthalmic in dogs include: Single dose for exam; short-term therapeutic. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenylephrine Ophthalmic is indicated in dogs for: Mydriasis without cycloplegia, conjunctival decongestion.
These are general warnings for Phenylephrine Ophthalmic across species; consult the dog dosing table above for species-specific guidance. 10% concentration can cause systemic hypertension — use 2.5% in small animals. Mydriasis without cycloplegia (pupil still accommodates). Avoid in narrow-angle glaucoma.
Why a species-specific page? Phenylephrine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| IV |
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.336 |
| correct blood volume then infuse 0.01 mg/kg very slowly i.v. q15min. Continuously monitor blood pressure if possible. |
| 0.01 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
| 0.1 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.