Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ciprofloxacin is dosed at 25 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023), Ciprofloxacin, p.295, DOGS row; superscript 1 = Papich MG. Ciprofloxacin pharmacokinetics in clinical canine patients. J Vet Intern Med. 2017;31(5):1508-1513. Corroborated by Papich, Saunders Handbook of Veterinary Drugs 4th ed p.189 ('Dogs • 25 mg/kg q24h PO') and Riviere & Papich, Veterinary Pharmacology and Therapeutics 10th ed p.983 ('Ciprofloxacin | 25 (oral) | recommended daily dose 25-30 once daily | Papich, 2012'). Ciprofloxacin is used in dogs for Gram-negative infections, UTI. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ciprofloxacin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cipro, Baytril
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 25 mg/kg | q24h | 7-14 days | Gram-negative infections, UTI | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023), Ciprofloxacin, p.295, DOGS row; superscript 1 = Papich MG. Ciprofloxacin pharmacokinetics in clinical canine patients. J Vet Intern Med. 2017;31(5):1508-1513. Corroborated by Papich, Saunders Handbook of Veterinary Drugs 4th ed p.189 ('Dogs • 25 mg/kg q24h PO') and Riviere & Papich, Veterinary Pharmacology and Therapeutics 10th ed p.983 ('Ciprofloxacin | 25 (oral) | recommended daily dose 25-30 once daily | Papich, 2012') |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Active metabolite of enrofloxacin in some species. Concentration-dependent killing.
Avoid in young growing animals (cartilage damage). May cause CNS stimulation. Drug interactions with antacids, sucralfate. Cats: retinal degeneration risk at high doses.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ciprofloxacin dose range in dogs, with cited source references: PO 25 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ciprofloxacin in dogs: PO.
Cited course lengths for Ciprofloxacin in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Ciprofloxacin is indicated in dogs for: Gram-negative infections, UTI.
These are general warnings for Ciprofloxacin across species; consult the dog dosing table above for species-specific guidance. Avoid in young growing animals (cartilage damage). May cause CNS stimulation. Drug interactions with antacids, sucralfate. Cats: retinal degeneration risk at high doses.
Why a species-specific page? Ciprofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.