Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ivermectin is used in dog for Generalized demodicosis (high dose), Heartworm prevention, generalized demodicosis, Ectoparasites, demodicosis, Sarcoptic mange. Routes documented in dog: PO, SC, TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 5 cited dose rules for Ivermectin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ivomec, Heartgard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.3–0.6 mg/kg | q24h | Until 2 negative skin scrapings 1 month apart | Generalized demodicosis (high dose) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.006–0.012 mg/kg | q30d | Monthly for prevention; daily for demodicosis (0.3-0.6 mg/kg) | Heartworm prevention, generalized demodicosis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| SC | 0.2–0.4 mg/kg | q7-14d | As needed | Ectoparasites, demodicosis | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| SC | 0.2–0.4 mg/kg | q14d | 2-4 treatments | Sarcoptic mange | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| TOPICAL | 0.3–0.4 mg/kg | q7d | 3-4 weekly treatments | Sarcoptic mange | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Potentiates glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing paralysis and death of parasites.
TOXIC to MDR1-mutant dogs (Collies, Shelties, Aussies) at elevated doses. DO NOT use in chelonians (turtles/tortoises). Narrow safety margin in some species. Test MDR1 status before use in herding breeds.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Ivermectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.