Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dorzolamide is dosed at 1 drop/eye TOPICAL q8h in dogs, per Gelatt KN, MacKay EO. Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs. Vet Ophthalmol. 2001;4:61-67. doi:10.1046/j.1463-5224.2001.00141.x; Cawrse MA, Ward DA, Hendrix DV. Effects of topical application of a 2% solution of dorzolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs. Am J Vet Res. 2001;62:859-863. doi:10.2460/ajvr.2001.62.859 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1389 (2026-08-01).. Dorzolamide is used in dogs for Glaucoma (IOP reduction). Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dorzolamide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Trusopt, Cosopt
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 1 drop/eye | q8h | Long-term | Glaucoma (IOP reduction) | Strong | Gelatt KN, MacKay EO. Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs. Vet Ophthalmol. 2001;4:61-67. doi:10.1046/j.1463-5224.2001.00141.x; Cawrse MA, Ward DA, Hendrix DV. Effects of topical application of a 2% solution of dorzolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs. Am J Vet Res. 2001;62:859-863. doi:10.2460/ajvr.2001.62.859 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1389 (2026-08-01). |
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Inhibits carbonic anhydrase II in the ciliary body, reducing aqueous humor production and lowering intraocular pressure.
Stinging on application. May be used alone or with timolol (Cosopt). Primary treatment for glaucoma in dogs. Less effective in cats and horses. Apply q8-12h.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dorzolamide dose range in dogs, with cited source references: TOPICAL 1 drop/eye q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dorzolamide in dogs: TOPICAL.
Cited course lengths for Dorzolamide in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Dorzolamide is indicated in dogs for: Glaucoma (IOP reduction).
These are general warnings for Dorzolamide across species; consult the dog dosing table above for species-specific guidance. Stinging on application. May be used alone or with timolol (Cosopt). Primary treatment for glaucoma in dogs. Less effective in cats and horses. Apply q8-12h.
Why a species-specific page? Dorzolamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.