Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tylosin GI is dosed at 10–25 mg/kg PO q12h in dogs, per Hall EJ. Antibiotic-responsive diarrhea in small animals. Vet Clin North Am Small Animal Pract. 2011;41(2):273-286. doi:10.1016/j.cvsm.2010.12.004; Weese JS. Bacterial enteritis in dogs and cats: diagnosis, therapy, and zoonotic potential. Vet Clin North Am Small Animal Pract. 2011;41(2):287-309. doi:10.1016/j.cvsm.2010.12.005 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1312 (2026-08-01).. Tylosin GI is used in dogs for Chronic diarrhea (tylosin-responsive diarrhea). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tylosin GI in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tylan Powder
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–25 mg/kg | q12h | Long-term | Chronic diarrhea (tylosin-responsive diarrhea) | Strong | Hall EJ. Antibiotic-responsive diarrhea in small animals. Vet Clin North Am Small Animal Pract. 2011;41(2):273-286. doi:10.1016/j.cvsm.2010.12.004; Weese JS. Bacterial enteritis in dogs and cats: diagnosis, therapy, and zoonotic potential. Vet Clin North Am Small Animal Pract. 2011;41(2):287-309. doi:10.1016/j.cvsm.2010.12.005 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1312 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Macrolide antibiotic with anti-inflammatory and immunomodulatory effects on GI mucosa. Mechanism for GI benefit not fully understood — may modify gut flora.
Widely used for chronic diarrhea in dogs responsive to tylosin. Very bitter — mix well with food. Long-term use common. Relapse on discontinuation typical.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tylosin GI dose range in dogs, with cited source references: PO 10–25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tylosin GI in dogs: PO.
Cited course lengths for Tylosin GI in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Tylosin GI is indicated in dogs for: Chronic diarrhea (tylosin-responsive diarrhea).
These are general warnings for Tylosin GI across species; consult the dog dosing table above for species-specific guidance. Widely used for chronic diarrhea in dogs responsive to tylosin. Very bitter — mix well with food. Long-term use common. Relapse on discontinuation typical.
Why a species-specific page? Tylosin GI pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.