Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tigilanol Tiglate is dosed at Dosing: 0.5 mg/cm3 tumor volume in dogs, per Stelfonta(R) [tigilanol tiglate] US prescribing information. Fort Worth, TX: Virbac AH; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1260 (2026-08-01).. Tigilanol Tiglate is used in dogs for Non-metastatic cutaneous mast cell tumors. Routes documented in dogs: INTRATUMORAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tigilanol Tiglate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Stelfonta
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRATUMORAL | Dosing: 0.5 mg/cm3 tumor volume | Single treatment; may repeat once at day 28 | One or two treatments | Non-metastatic cutaneous mast cell tumors | Strong | Stelfonta(R) [tigilanol tiglate] US prescribing information. Fort Worth, TX: Virbac AH; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1260 (2026-08-01). |
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Activates protein kinase C, disrupting tumor vasculature and causing hemorrhagic necrosis. Also stimulates innate immune response against tumor cells.
Dogs only. For non-metastatic mast cell tumors (cutaneous/SC). Wound at injection site expected — heals by second intention. Sedation/anesthesia required for injection.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tigilanol Tiglate dose range in dogs, with cited source references: INTRATUMORAL Dosing: 0.5 mg/cm3 tumor volume Single treatment; may repeat once at day 28. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tigilanol Tiglate in dogs: INTRATUMORAL.
Cited course lengths for Tigilanol Tiglate in dogs include: One or two treatments. Duration depends on the indication — match it to the specific dose rule in the table above.
Tigilanol Tiglate is indicated in dogs for: Non-metastatic cutaneous mast cell tumors.
These are general warnings for Tigilanol Tiglate across species; consult the dog dosing table above for species-specific guidance. Dogs only. For non-metastatic mast cell tumors (cutaneous/SC). Wound at injection site expected — heals by second intention. Sedation/anesthesia required for injection.
Why a species-specific page? Tigilanol Tiglate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.