ExoticRx · exoticrx.com/drugs/tigilanol-tiglate
US brand names:Stelfonta
Activates protein kinase C, disrupting tumor vasculature and causing hemorrhagic necrosis. Also stimulates innate immune response against tumor cells.
Dogs only. For non-metastatic mast cell tumors (cutaneous/SC). Wound at injection site expected — heals by second intention. Sedation/anesthesia required for injection.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | INTRATUMORAL | See the cited source for the printed regimen | Single treatment; may repeat once at day 28 | Strong | Stelfonta(R) [tigilanol tiglate] US prescribing information. Fort Worth, TX: Virbac AH; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1260 (2026-08-01). — Plumb's 10th ed (held) printed p.1232, Tigilanol Tiglate monograph spanning p.1232-1234; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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