Bedaquiline for Cat
Cat · Felis catus · typical adult weight 2.50–7.00 kg
Bedaquiline is used in cat for MDR mycobacterial infections. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Bedaquiline in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Sirturo
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q24h x 2wks, then q48h | 24 weeks (combination therapy) | MDR mycobacterial infections | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Inhibits mycobacterial ATP synthase proton pump, disrupting energy production. Novel target specific to mycobacteria.
Side effects & warnings
QTc prolongation. Hepatotoxicity. Very long half-life (~5 months). Reserved for MDR-TB. No veterinary data.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with cat dosing
Bedaquiline dosing in other species
Why a species-specific page? Bedaquiline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.