Question 1

What is Bithionol used for?

Accepted Answer

Bithionol is indicated for: Liver fluke (Opisthorchis/Platynosomum), Liver fluke (Paragonimus).

Question 2

What routes can Bithionol be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Bithionol dosing data?

Accepted Answer

Bithionol dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Bithionol a controlled substance?

Accepted Answer

Bithionol is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Bithionol?

Accepted Answer

GI upset common. Photosensitivity may occur. Limited veterinary use — primarily for fluke infections not responsive to other agents.

Question 6

What are the side effects of Bithionol?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Bithionol: GI upset common. Photosensitivity may occur. Limited veterinary use — primarily for fluke infections not responsive to other agents.

Question 7

How does Bithionol work?

Accepted Answer

Uncouples oxidative phosphorylation in trematodes and cestodes, inhibiting parasite energy production.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	30–50 mg/kg	q48h for 10-15 doses	Weak	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	30–50 mg/kg	q48h for 10-15 doses	Weak	Plumb's Veterinary Drug Handbook, 9th Ed

Bithionol

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Bithionol dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published source

Sample dosing (2 of 2 cited rules)

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