Cat · Felis catus · typical adult weight 2.50–7.00 kg
Brimonidine Ophthalmic is used in cats for CONTRAINDICATED in cats. Routes documented in cats: TOPICAL (ophthalmic). A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Brimonidine Ophthalmic in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alphagan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | TOXIC IN CATS — causes severe sedation, bradycardia, hypotension, hypothermiamax 0 mg total | CONTRAINDICATED | TOXIC | CONTRAINDICATED in cats | Strong | Riviere JE & Papich MG, Veterinary Pharmacology and Therapeutics, p.165 ('not recommended for veterinary patients'); corroborated for cats specifically by Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) p.1376, whose cat-specific adverse-effect paragraph rests on in-cat primary studies (Ogata et al., Vet Anaesth Analg 2017;44:1091-1100, sedative and physiological effects in healthy cats; Kanda et al., J Feline Med Surg 2019) — Plumb's 10th ed (held) printed p.1349, Brimonidine Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829 |
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Alpha-2 adrenergic agonist that decreases aqueous humor production and increases uveoscleral outflow. Also neuroprotective to retinal ganglion cells.
TOXIC in cats and small dogs (systemic alpha-2 effects: sedation, bradycardia, hypotension). Avoid in cats. Use with caution in small dogs. Monitor for CNS depression.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Brimonidine Ophthalmic dose range in cats, with cited source references: TOPICAL (ophthalmic) TOXIC IN CATS — causes severe sedation, bradycardia, hypotension, hypothermia CONTRAINDICATED. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Brimonidine Ophthalmic in cats: TOPICAL (ophthalmic).
Cited course lengths for Brimonidine Ophthalmic in cats include: TOXIC. Duration depends on the indication — match it to the specific dose rule in the table above.
Brimonidine Ophthalmic is indicated in cats for: CONTRAINDICATED in cats.
These are general warnings for Brimonidine Ophthalmic across species; consult the cat dosing table above for species-specific guidance. TOXIC in cats and small dogs (systemic alpha-2 effects: sedation, bradycardia, hypotension). Avoid in cats. Use with caution in small dogs. Monitor for CNS depression.
Why a species-specific page? Brimonidine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.