ExoticRx · exoticrx.com/drugs/canine-da2pp-vaccine
US brand names:Nobivac DAPPv, Vanguard Plus 5
Canine DA2PP Vaccine is dosed at 1 dose SC q3-4wk from 6-16wk; booster 1yr then q3yr in dogs, per 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05. Verify against current literature before clinical use.
Modified live virus vaccine stimulating active immunity against canine distemper, adenovirus type 2, parainfluenza, and parvovirus.
Do not use in immunocompromised or pregnant animals. Administer per AAHA guidelines. Allergic reactions possible — observe 15-30 min post-vaccination.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 1 dose | q3-4wk from 6-16wk; booster 1yr then q3yr | Strong | 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05 |
| Dog (Domestic) | SC | 1 dose | At intake, then q2wk until 20 weeks of age | Strong | 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05; ASV Guidelines |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.