Amphibian · Xenopus laevis · typical adult weight 0.05–0.25 kg
Chloramphenicol is dosed at 10–20 mg/l bath not stated in the cited source in african clawed frogs, per Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.84. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712. Chloramphenicol (Antibiotic) has cited veterinary dosing for african clawed frogs. Routes documented in african clawed frogs: bath, s.c.. A typical adult african clawed frog weighs 0.05–0.25 kg. ExoticRx lists 2 cited dose rules for Chloramphenicol in african clawed frogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| bath | 10–20 mg/l | not stated in the cited source | — | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.84. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712 |
| s.c. | 50 mg/kg | q12-24h | — | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.84. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 1 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | mg/kg topically (applied as Chlorsig 1% ointme [Sigma], which also contains paraffin and wool -30 mg/L (10-30 ppm) as continuous bath replace fresh daily for up to 30 days52 mg/L b |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 50 | SC | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.84 | 50 mg/kg s.c., i.m., intracoelomic q12-24h or 10-20 mg/l as a bath b,c,d |
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Binds to 50S ribosomal subunit, inhibiting peptidyl transferase and bacterial protein synthesis. Bacteriostatic.
Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Species-specific contraindications and adverse-reaction reports for african clawed frogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Chloramphenicol dose ranges in african clawed frogs, with cited source references: bath 10–20 mg/l not stated in the cited source; s.c. 50 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Chloramphenicol in african clawed frogs: bath, s.c..
These are general warnings for Chloramphenicol across species; consult the african clawed frog dosing table above for species-specific guidance. Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Why a species-specific page? Chloramphenicol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in african clawed frogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 40 |
| PO |
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 |
| 40 mg/kg PO, SC, IM q24h, or 20 mg/ kg PO, SC, IM q12h90 Most species/20 mg/kg may be given q24h in larger crocodilians |
| 50 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 50 mg/kg SC, IM, ICe q12-24h52 20 mg/L batha changed daily52 Caution: even miniscule exposures carries risk of aplastic anemia in susceptible individuals; wear disposable gloves wh |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 10–20 | IMMERSION | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.84 | 50 mg/kg s.c., i.m., intracoelomic q12-24h or 10-20 mg/l as a bath b,c,d |
| 20 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 3.2 | 20 mg/L continuous bath × 14 days |
| 30 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 3.2 | 30 mg/L continuous bath for up to 30 days |
| 52 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | mg/kg topically (applied as Chlorsig 1% ointme [Sigma], which also contains paraffin and wool -30 mg/L (10-30 ppm) as continuous bath replace fresh daily for up to 30 days52 mg/L b |
| 30 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | mg/kg topically (applied as Chlorsig 1% ointme [Sigma], which also contains paraffin and wool -30 mg/L (10-30 ppm) as continuous bath replace fresh daily for up to 30 days52 mg/L b |
| 20 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 50 mg/kg SC, IM, ICe q12-24h52 20 mg/L batha changed daily52 Caution: even miniscule exposures carries risk of aplastic anemia in susceptible individuals; wear disposable gloves wh |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.