Amphibian · Xenopus laevis · typical adult weight 0.05–0.25 kg
Metronidazole is dosed at 50 mg/l bath immersion/bath — see duration in african clawed frogs, per Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.217. — LOCATOR CONVENTION 2026-08-07: the bare 'p.217' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.203; verified by finding the drug named there. If you are holding the book, turn to p.203. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712. Metronidazole is used in african clawed frogs for up to 24 hours. Routes documented in african clawed frogs: bath, p.o.. A typical adult african clawed frog weighs 0.05–0.25 kg. ExoticRx lists 2 cited dose rules for Metronidazole in african clawed frogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Flagyl
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| bath | 50 mg/l | immersion/bath — see duration | up to 24 hours | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.217. — LOCATOR CONVENTION 2026-08-07: the bare 'p.217' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.203; verified by finding the drug named there. If you are holding the book, turn to p.203. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712 |
| p.o. | 50 mg/kg | q24h | up to 24 hours | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.217. — LOCATOR CONVENTION 2026-08-07: the bare 'p.217' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.203; verified by finding the drug named there. If you are holding the book, turn to p.203. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 50 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.217 | 50 mg/kg p.o. q24h for 3-5 days or 50 mg/l as a bath for up to 24 hours |
| 100–150 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 3.3 | 10 mg/kg PO q24h × 5-10 days 100 mg/kg PO q3d;90 100-150 mg/kg PO, repeat in 2-3 wk or prn |
| 20–50 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 3.1 | 12-60 mg/kg topically q24h × 5-10 days 20-50 mg/kg PO q24- 48h 50 mg/L × 24 hr bath |
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These ranges are per kg. Enter your african clawed frog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Disrupts DNA structure in anaerobic organisms via reduction of nitro group, forming cytotoxic intermediates.
Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Species-specific contraindications and adverse-reaction reports for african clawed frogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Metronidazole dose ranges in african clawed frogs, with cited source references: bath 50 mg/l immersion/bath — see duration; p.o. 50 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Metronidazole in african clawed frogs: bath, p.o..
Metronidazole is indicated in african clawed frogs for: up to 24 hours.
These are general warnings for Metronidazole across species; consult the african clawed frog dosing table above for species-specific guidance. Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Why a species-specific page? Metronidazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in african clawed frogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 10 |
| PO |
| Carpenter's Exotic Animal Formulary, 6th edTable 3.3 |
| 10 mg/kg PO q24h × 5-10 days 100 mg/kg PO q3d;90 100-150 mg/kg PO, repeat in 2-3 wk or prn |
| 100 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 3.3 | 10 mg/kg PO q24h × 5-10 days 100 mg/kg PO q3d;90 100-150 mg/kg PO, repeat in 2-3 wk or prn |
| 12–60 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 3.1 | 12-60 mg/kg topically q24h × 5-10 days 20-50 mg/kg PO q24- 48h 50 mg/L × 24 hr bath |
| 12 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 12 mg/kg topically q24h × 5-10 days52 For chronic diarrhea |
| 60 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 60 mg/kg topically q24h × 3 days52 Anaerobic infections |
| 100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 100 mg/kg PO q3d52 Protozoa |
| 100–150 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 100-150 mg/kg PO, repeat in 2-3 wk or prn52 Protozoa (i.e., Entamoeba, Hexamita, Opalina) |
| 12.5–50 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.8 | 12.5-50 mg/kg PO88 Most species/appetite stimulant (anecdotal; presumably associated with antiprotozoal activity) |
| 20 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 20 mg/kg PO q48h × ≥ 7 days99 Most species/anaerobes |
| 50 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 50 mg/kg PO q24h × 7-14 days167 Most species/may be administered concurrently with amikacin for broader spectrum; because of potential side effects at this dose, a lower dose may b |
| 40–100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 40-100 mg/kg PO, repeat in 10-14 days88 Most species/flagellate overgrowth |
| 10 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 10 mg/kg PO q24h × 5-10 days52 Protozoa; for unfamiliar or sensitive species |
| 10 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 10 mg/kg IV q24h × 2 days52 Anaerobic infections |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 50 | IMMERSION | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.217 | 50 mg/kg p.o. q24h for 3-5 days or 50 mg/l as a bath for up to 24 hours |
| 50 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 3.1 | 12-60 mg/kg topically q24h × 5-10 days 20-50 mg/kg PO q24- 48h 50 mg/L × 24 hr bath |
| 50 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 50 mg/L × 24 hr bath52 500 mg/100 g feed × 3-4 treatments52 Aquatic amphibians/protozoa Ciliates |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.