Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Cimetidine is dosed at 5–10 mg/kg PO, SC, IM, IV q6-12h in mice, per 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01, PENDING REVIEW). Cimetidine is used in mice for Gastric/duodenal ulceration; esophagitis; gastroesophageal reflux (H2-blocker). Routes documented in mice: PO, SC, IM, IV. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 1 cited dose rule for Cimetidine in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tagamet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, SC, IM, IV | 5–10 mg/kg | q6-12h | Gastric/duodenal ulceration; esophagitis; gastroesophageal reflux (H2-blocker) | Moderate | 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01, PENDING REVIEW) |
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Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cimetidine dose range in mice, with cited source references: PO, SC, IM, IV 5–10 mg/kg q6-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cimetidine in mice: PO, SC, IM, IV.
Cimetidine is indicated in mice for: Gastric/duodenal ulceration; esophagitis; gastroesophageal reflux (H2-blocker).
These are general warnings for Cimetidine across species; consult the mouse dosing table above for species-specific guidance. Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Why a species-specific page? Cimetidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.