Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Cimetidine is dosed at 5–10 mg/kg PO q6-12h in rabbits, per Carpenter's Exotic Animal Formulary, 6th Ed, Table 10.10 'Miscellaneous Agents Used in Rabbits' -- 'Cimetidine 5-10 mg/kg PO, SC, IM, IV q6-12h; Gastric and duodenal ulcers' — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits). Verify against current literature before clinical use.
Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Side effects & warnings
Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Species with Cimetidine dosing data (21 dose rules)
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 21 cited rules)
A dog/cat sample is shown here. Cited dosing for all 21 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Plumb's 10th ed printed p.263, Cimetidine monograph spanning p.263-264.Compilation only — we have not located an independent source that prints this figure.
Plumb's 10th ed printed p.263, Cimetidine monograph spanning p.263-264.Compilation only — we have not located an independent source that prints this figure.
· 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.799 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.7 (Miscellaneous Agents Used in Rodents).
· 45. Lightfoot T. Therapeutics of African pygmy hedgehogs and prairie dogs. Vet Clin North Am Exot Anim Pract. 2000;3:155-172. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.744 doi:10.1016/s1094-9194(17)30099-3 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.7 (Miscellaneous Agents Used in Hedgehogs).
· 63. Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.272 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles).
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